Anxiety and its impact on the trajectory of normal vs. abnormal aging. Lead Investigator: Mary Jeffrey Institution : Nova Southeastern University E-Mail : mgtjeffrey@gmail.com Proposal ID : 677 Proposal Description: This project would use NACC data to assess levels of anxiety as shown by the NPI, and how anxiety impacts subjective and objective memory or how informants/participants feel about their memory as shown by the GDS and Clinician Judgement of Symptoms, and the neuropsychological batteries that objectively measure memory issues. I???m interested to see if anxiety moderates, and hypothetically, accelerates this process. In addition, I would be interested to see if APOE would be involved.